Jae Hun Shin

Dr. Jae Hun Shin is an Associate Professor in the Integrated Science & Engineering Division at Yonsei University, where he leads the Tumor Immunology Lab. He also serves as an Adjunct Assistant Professor in the Section of Endocrinology, Internal Medicine at Yale University.

Dr. Shin received his Ph.D. in Immunobiology from Yale University and subsequently completed postdoctoral training there. His research focuses on a process called trogocytosis — the transfer of membrane fragments between cells — and how cancer cells exploit this mechanism to acquire immune regulatory molecules from T cells, thereby evading anti-tumor immunity.

His laboratory employs a multidisciplinary approach combining mass spectrometry, RNA sequencing, CRISPR/Cas9 screening, organoid models, and in vivo systems to identify immunotherapeutic targets and develop novel cancer immunotherapies including mRNA-LNP and CAR-T cell strategies.